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1. Polyphenols Can Reduce Oxidative Stress and Inflammation
2. Healthy Keto?
3. Agent Orange and Neuropathy (nerve damage), Autoimmune and Other Problems
4. What causes Gastritis?

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Polyphenols Can Reduce Oxidative Stress and Inflammation By Qgenics on Aug 26, 2021 11:29 am

What is oxidative stress?

The imbalance between the formation and accumulation of reactive oxygen species (ROS) in cells and tissues and the biological system’s ability to detoxify these reactive products lead to oxidative stress[1]. Reactive oxygen species are produced in the body by oxygen metabolism and environmental factors like air pollution. ROS significantly increase the risk of oxidative stress[2]. When there are more ROS present than can be kept in balance by antioxidants, the ROS can start doing damage to fatty tissue, DNA, and proteins in the body. Proteins, lipids, and DNA make up a large part of the body, so that damage can lead to a vast number of diseases over time, including neurodegenerative diseases and inflammatory diseases. The inflammatory diseases include skin problems.

What is inflammation?

Inflammation is a natural protective mechanism against microbial and viral infections, allergen exposure, radiation and toxic chemicals, autoimmune and chronic diseases, obesity, alcohol and tobacco use, and a high-calorie diet. Oxidative stress and a range of protein oxidations are common symptoms of chronic illnesses connected to increased ROS generation [3]. In addition, protein oxidation results in the production of inflammatory agents in the body that cause inflammation.

The link between oxidative stress and inflammation

Oxidative stress and inflammation are closely related. In many pathological conditions, both processes are present simultaneously. Numerous chronic diseases are associated with an increase in the body’s inflammatory response when exposed to oxidative stress[4]. During the inflammatory process, particular cells produce large amounts of ROS to kill the invading agents. Thus, they can induce localized oxidative stress and tissue injury.

Oxidative stress and inflammation are underlying factors in skin problems

Some chronic inflammatory skin conditions include acne, dermatitis, drug rashes, psoriasis and eczema. Psoriasis and eczema are a significant issue today. They can run in a family, but they are most often triggered by allergens, extreme temperatures, and most often stress.

What are polyphenols?

Polyphenols are antioxidants which can neutralize harmful free radicals that would otherwise damage cells and increase your risk of chronic conditions, such as psoriasis, eczema, diabetes and heart disease. Polyphenols help many chronic conditions by reducing inflammation[5].

How do polyphenols reduce oxidative stress and inflammation?
Polyphenols have antioxidant activity that prevents damage of body cells from reactive oxygen species. Polyphenols exert their antioxidant ability by various mechanisms, including 1) stopping the enzymes that produce reactive oxygen species, 2) reducing the action of reactive oxygen species, and 3) improving body antioxidant defense mechanisms [6].

Furthermore, polyphenols have antiproliferative properties that mean they can prevent the spread of inflammation in the body.
Sources of polyphenols

Some sources of polyphenols are as follows:

Olives: polyphenols from olives are one of the most potent antioxidants and can actively reduce oxidative stress and inflammation.
Berries.
Herbs and Spices.
Cocoa Powder.
Nuts.
Flaxseeds.
Vegetables.

Inflammation Relief is a 100% natural supplement of organic polyphenols formulated to reduce inflammation and support healthier skin.

References:
1. Pizzino G, Irrera N, Cucinotta M, et al. Oxidative Stress: Harms and Benefits for Human Health. Oxid Med Cell Longev. 2017;2017:8416763. doi:10.1155/2017/8416763
2. Hussain T, Tan B, Yin Y, Blachier F, Tossou MC, Rahu N. Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?. Oxid Med Cell Longev. 2016;2016:7432797. doi:10.1155/2016/7432797
3.Salzano S, Checconi P, Hanschmann EM, Lillig CH, Bowler LD, Chan P, Vaudry D, Mengozzi M, Coppo L, Sacre S, Atkuri KR, Sahaf B, Herzenberg LA, Herzenberg LA, Mullen L, Ghezzi P. Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal. Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12157-62. doi: 10.1073/pnas.1401712111. Epub 2014 Aug 5. PMID: 25097261; PMCID: PMC4143057.
4. Popa-Wagner A, Mitran S, Sivanesan S, Chang E, Buga AM. ROS and brain diseases: the good, the bad, and the ugly. Oxid Med Cell Longev. 2013;2013:963520. doi: 10.1155/2013/963520. Epub 2013 Dec 5. PMID: 24381719; PMCID: PMC3871919.
5. Cory H, Passarelli S, Szeto J, Tamez M, Mattei J. The Role of Polyphenols in Human Health and Food Systems: A Mini-Review. Front Nutr. 2018;5:87. Published 2018 Sep 21. doi:10.3389/fnut.2018.00087
6. Perron, N.R., Brumaghim, J.L. A Review of the Antioxidant Mechanisms of Polyphenol Compounds Related to Iron Binding. Cell Biochem Biophys 53, 75–100 (2009). https://doi.org/10.1007/s12013-009-9043-x

Healthy Keto?

You have probably heard of Keto and it seems that there are more definitions of Keto then one can count. I also heard that people can't do Keto because their liver can't take all the fat.

Well, the liver is the problem and the Keto found the problem. Thus, there is alway ways to, and you should, build liver health.

Here is some information on that and our recommendations for The Liver

Although the common denominator of all keto diets is low net carbs to induce ketosis, not all keto diets are created equal.

In fact, traditional ketogenic diets do not differentiate the type of food. Many times they include processed, genetically modified foods, gluten products, unhealthy trans fats, and synthetic vitamins. This gives keto a bad rap. Traditional low-carb, high-fat keto's primary goal is usually rapid weight loss or a reduction of epilepsy symptoms, and not necessarily good nutrition. As a result, you could lose weight or reduce certain symptoms but become less healthy overall.

Let's talk about Healthy Keto - here is a article that tells you what healthy keto really is and you can decide for yourself.

Agent Orange and Neuropathy (nerve damage), Autoimmune and Other Problems

How it happened and what can be done for relief

Almost 20 million gallons of herbicides were dumped on Vietnam between 1962 and 1971 to kill jungle foliage with the aim of exposing enemy targets.  It was used to prevent the communist forces from using the jungle for cover, to destroy their food supply and to clear areas of the jungle for U.S. occupation. 

The U.S. Army heavily sprayed areas of inland forest in the demarcation zone, along the borders of Cambodia, Laos and South Vietnam and areas north and northwest of Saigon. There was also heavy spraying in the mangrove forests on the southernmost peninsula of Vietnam and along the major shipping channels southeast of Saigon.

Shortly following their military service in Vietnam, some veterans reported a variety of health problems and concerns which some of them attributed to exposure to Agent Orange or other herbicides.

Agent Orange contains dioxin, which has known biological and physical effects. 

Both Vietnamese citizens and war veterans have experienced health problems as a result of Agent Orange exposure. Health problems include birth defects, skin diseases and peripheral neuropathy. Agent Orange may also be responsible for some instances of Parkinson's and heart diseases.

Physical and Neurological Effects of Agent Orange

According to the World Health Organization, short-term exposure to high levels of dioxins causes skin damage and altered liver function. Long-term exposure causes immune system impairment and damage to the nervous, endocrine and reproductive systems in developing fetuses. Dioxin is also a known carcinogen.

According to the VA, there are several diseases associated specifically with Agent Orange exposure, including Hodgkin's disease, chronic lymphocytic leukemia and type 2 diabetes.  Agent Orange also causes a neurological disorder known as acute and subacute peripheral neuropathy. Agent Orange has recently been linked to an elevated risk for Parkinson's, another neurological disorder. Symptoms and effects of Agent Orange exposure may take months or even years to appear.

Autoimmune problems - Studies on Veterans-Agent Orange Immune System Disorders

Acute and Subacute Peripheral Neuropathy

Peripheral neuropathy is damage to the peripheral nervous system, which consists of the nerves that transmit information from the central nervous system to the rest of the body. The peripheral nervous system carries sensory messages and motor impulses. When this system is damaged, it can cause numbness and weakness in the limbs and nerve pain. The peripheral nervous system also controls the heartbeat, and damage to this system could result in heart rate irregularities.

RECOMMENDED: 

If you do have Neuropathy from Agent Orange.

What can you do about neuropathy or nerve damage?

Treatment for Neuropathy

There are many medications, and other remedies that can bring you relief, you can read about them in this article  Neuropathy treatments

What can you do?

Take a Quiz: Am I doing everything I can to daily help my neuropathy?

Find out what lifestyle changes will help, take the quiz and get our suggestions and get our assistance on what you can do.

Take Our   Quiz

Lasting Relief:

None of the various neuropathy treatments will build healthy nerves.  You can cover up the symptoms and you can increase circulation and you can make a person feel less pain, etc., but if you build healthy nerves, there will not be any symptoms (healthy nerves don't hurt, tingle, burn, are not numb, etc.) and the relief will be lasting.  

Building Healthy Nerves* 

Healthy sensory nerves mean that they are not painful. Healthy nerves means that they communicate and don't send wrong signals such as burning, hot and cold, tingling when there is no reason for it. Healthy motor nerves mean that they relay messages from the brain to the muscle so that they move correctly. Nerves need to be healthy to function properly. 

The body needs specific nutrients (vitamins) to be able to build healthy nerves. 

It may not give immediate relief (although many do feel changes in the first week) as the vitamins are working at a cellular level, but it does address the actual problem, builds healthy nerves and brings lasting relief.  

(For temporary relief while building healthy nerves, go to Pain Relief Formula)

What can be done for lasting relief?

Find out how to  build Healthy Nerves

*Studies & Research on Nerve Health

Is it Agent Orange or is it a Fungal Infection from Viet Nam?

The information on this comes from a Viet Nam vet who was very sick when he got back.  He was exposed to Agent Orange but didn't have any adverse reaction to it.  He started researching and found that fungus was the cause of his problem.   He was exposed to fungus in Viet Nam.

Here is his website and the Science of Fungus

There are many Agent Orange Support Groups.  . There is a Facebook site Agent Orange Education Campaign   There are lists there of other groups as well.

What causes Gastritis?

Here is an educational video to give you a good understandng of this problem. Find out how to help improve gastritis naturally.

Gastritis

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