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1. Reanalysis of Popular Antidepressant Trial Uncovers
Reporting Flaws
2. Research regarding the Gut-Brain Connection in Children with Special Needs
3. Nutritional supplements can cut hospital readmission rates
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Reanalysis of Popular Antidepressant Trial Uncovers
Reporting Flaws
A reanalysis of a study found that fluoxetine alone showed no measurable benefit over placebo in treating adolescent depression after 12 weeks
Researchers uncovered 11 additional suicide-related events that were hidden or misclassified, bringing the total to 21 serious incidents
Statistical tactics and selective reporting made fluoxetine appear safer and more effective than it really was in clinical trials
A different reanalysis mentioned that adverse events and many side effects were minimized or excluded from the original reports
Improving gut health, getting regular exercise, and optimizing vitamin D are viable approaches for treating depression
Once in a while, the findings of a particular study make such a big impact in the medical industry that it influences recommendations for many years to come. One notable example is the Treatment for Adolescents with Depression Study (TADS), which was published in 2004.
Read more mercola.com "Reanalysis of Popular Antidepressant Trial Uncovers
Reporting Flaws" 9/16/2025
The Gut-Brain Connection in Children with Special Needs
Many children with special needs often struggle with stomach and digestive problems. This has led researchers to take a closer look at the gut microbiome - the trillions of bacteria living in our intestines and how it may play a role in child development.
Studies have found that when the gut’s balance of bacteria is “off,” it may also affect the brain, emotions, and social behaviors. While scientists don’t yet fully understand the exact link, they believe the gut and brain are closely connected through what’s called the microbiota-gut-brain axis.
So, how might the gut affect these symptoms?
*Leaky gut: Changes in gut bacteria may make the intestines more “permeable,” letting substances slip into the bloodstream that normally wouldn’t.
*Immune function: Gut imbalances can affect the immune system, possibly triggering inflammation.
*Brain chemicals: Gut bacteria create substances that may influence brain function and behavior.
*Gene activity: Some research even suggests gut microbes might affect how certain genes are “switched on or off,” which could play a role in these same symptoms.
Because of these discoveries, scientists are exploring new therapies that target the microbiome. These include:
*Probiotics and prebiotics* (to restore healthy bacteria)
*Dietary changes and supplements
Early results are promising.
Why it matters
This growing field of research shows that gut health may be more closely tied to brain health than we ever realized.
Understanding and supporting the gut microbiome could open up new ways to ease certain challenges faced by special needs children.
Nutritional supplements can cut hospital readmission rates.
Hey, it’s Dr. Martin here…
Let me share something that I was thinking about the other day. A study out of Stanford University, 11 years in the making and the headline read:
Nutritional supplements can cut hospital readmission rates.
Now, let that sink in for a second. One in five patients in the U.S. (Same for Canada) ends up back in the hospital within the same year. That costs taxpayers over 17 billion dollars.
The two biggest reasons for readmission? Congestive heart failure, and heart attacks.
So here’s what this 11-year study tested. When patients were discharged, they gave them supplement not more prescriptions. Supplements.
And here’s the short list:
B12. Vitamin D. Omega-3. Magnesium.
That’s it.
Now I know what you’re thinking… “Doc, those sound familiar.” Yeah… because I’ve been shouting about them for years.
Your heart isn’t just a pump. It’s an electrical grid. It needs the right spark plugs to fire properly.
Magnesium, for example, is the “relax” mineral. Your heart goes into spasm?
Magnesium calms it. Blood pressure spikes? Magnesium relaxes the vessels.
Adrenals in overdrive? Magnesium helps you unwind.
But here’s the crazy part.
You’ll almost never hear this from a cardiologist. Even though get this, many of them take supplements themselves.
I once asked a room of 150 cardiologists how many used omega-3. Sixty to seventy percent put their hands up. Then I asked how many recommended it to their patients. Almost every hand went down.
That tells you everything you need to know about the system.
And yet, this study proved what we already knew.
Hospital readmissions dropped by 10% in heart failure cases.
Heart attack recurrences dropped by 12%.
Overall, hospital stays shortened by 16%.
All from nutrients the body desperately needs.
Now, let’s be clear, I’m not against medication when it’s needed. But you’ll never drug your way out of a deficiency.
Think of it this way. If your heart is running on empty, giving another pill is like painting over rust. You might hide the problem for a while, but the corrosion is still spreading.
Supplements aren’t magic.
They’re fuel.
They’re spark plugs.
They’re the wires that keep the electrical grid humming.
So don’t wait until you’re being wheeled out of a hospital bed.
Prevention starts now.
Eat real food.
Cut the sugar.
Get your vitamin D.
Add DHA…
B12…
Magnesium.
Because if it can keep people from being readmitted, imagine what it can do to keep you out of the hospital in the first place.
Talk soon,
Dr. Martin (martinclinic.com)
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